Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.51 |
| ▸ | CASR | P41180 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13010630 | 0.78 | KIF11 (0.79) | KIF11KDM4EALDH1A1GAA | |
| SCHEMBL31549973 | 0.78 | KIF11 (0.79) | KIF11KDM4EALDH1A1GAA | |
| SCHEMBL28675865 | 0.77 | KIF11 (0.62) | KIF11KDM4EALDH1A1GAAVDR | |
| SCHEMBL10114699 | 0.77 | MEN1 (0.46) | KIF11CASRCYP1A2ADRA2AADRA2B | |
| SCHEMBL21376875 | 0.76 | KIF11 (0.62) | KIF11KDM4EALDH1A1GAA | |
| SCHEMBL11019542 | 0.75 | SLC6A4 (0.50) | ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2A | |
| SCHEMBL19788308 | 0.75 | KIF11 (0.51) | KIF11KDM4EALDH1A1 | |
| SCHEMBL28013776 | 0.75 | ALDH1A1 (0.56) | ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2A | |
| SCHEMBL6492246 | 0.74 | AHR (0.44) | KIF11CASRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL22417035 | 0.73 | KIF11 (0.56) | KIF11CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077345-A1 | CARBAZOLE NOVOLAK RESIN | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-03-29 | — | — | US | disclosed |