SCHEMBL28675871

SCHEMBL28675871

CCCCC(CC)CNCCCCCN

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.62
TSHR P16473 3/20 0.62
CYP3A4 P08684 2/20 0.62
TDP1 Q9NUW8 1/20 0.48
KDM4E B2RXH2 1/20 0.42
DNM1 Q05193 8/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
EPHX1 P07099 1/20 0.41
GNAI3 P08754 1/20 0.41
GNAO1 P09471 1/20 0.41
GNAI1 P63096 1/20 0.41
CA12 O43570 1/20 0.40
F13A1 P00488 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CYP1A2 P05177 1/20 0.40
CA3 P07451 1/20 0.40
CYP2C9 P11712 1/20 0.40
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9496210 1.00 ALDH1A1 (0.62) ALDH1A1TSHRCYP3A4TDP1KDM4E
SCHEMBL965000 1.00 ALDH1A1 (0.62) ALDH1A1TSHRCYP3A4TDP1KDM4E
SCHEMBL19102876 0.95 ALDH1A1 (0.55) ALDH1A1TSHRCYP3A4TDP1DNM1
SCHEMBL197248 0.93 ALDH1A1 (0.67) ALDH1A1TSHRCYP3A4TDP1KDM4E
SCHEMBL29057251 0.91 ALDH1A1 (0.60) ALDH1A1TSHRCYP3A4TDP1KDM4E
SCHEMBL9816844 0.91 ALDH1A1 (0.56) ALDH1A1TSHRCYP3A4TDP1KDM4E
SCHEMBL7785935 0.91 ALDH1A1 (0.75) ALDH1A1TSHRCYP3A4TDP1KDM4E
SCHEMBL7884018 0.89 ALDH1A1 (0.62) ALDH1A1TSHRCYP3A4TDP1KDM4E
SCHEMBL28358371 0.89 ALDH1A1 (0.62) ALDH1A1TSHRCYP3A4TDP1KDM4E
SCHEMBL19103006 0.89 GNAI3 (0.47) ALDH1A1TSHRCYP3A4DNM1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113811523-A Process for the preparation of 2, 2-dialkyl-3-acyloxypropionaldehyde SIKA技术股份公司 2021-12-17 CN disclosed