SCHEMBL2867589

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2862635	0.84	DGAT2 (0.56)	DGAT2GAAHPGDROCK2NPC1
	SCHEMBL2872610	0.83	DGAT2 (0.56)	DGAT2GAAHPGDROCK2NPC1
	SCHEMBL2868742	0.83	TTK (0.57)	DGAT2GAAROCK2CSNK1DMAPT
	SCHEMBL2864651	0.82	APEX1 (0.52)	HPGDROCK2MAPTUSP2ALDH1A1
	SCHEMBL13198231	0.78	MAPT (0.51)	ROCK2CSNK1DMAPTAURKAMMP13
	SCHEMBL2864882	0.78	TP53 (0.53)	HPGDROCK2MAPTUSP2ALDH1A1
	SCHEMBL2858848	0.78	ROCK2 (0.59)	HPGDROCK2MAPTAURKAMMP13
	SCHEMBL2863001	0.77	NTRK1 (0.56)	DGAT2GAAHPGDROCK2CSNK1D
	SCHEMBL2864166	0.77	NTRK1 (0.49)	NTRK1LRRK2
	SCHEMBL13198273	0.75	DGAT2 (0.50)	DGAT2ROCK2CSNK1DNTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.