Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | PGK2 | P07205 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10202598 | 0.85 | MAPK1 (0.46) | TSHRALDH1A1PTPN1MAPK1KCNN4 | |
| SCHEMBL914885 | 0.78 | ALDH1A1 (0.50) | TSHRALDH1A1PTPN1MAPK1KCNN4 | |
| SCHEMBL17763368 | 0.78 | TSHR (0.50) | TSHRALDH1A1PTPN1MAPK1KCNN4 | |
| SCHEMBL10496222 | 0.77 | TSHR (0.55) | TSHRALDH1A1PTPN1MAPK1KCNN4 | |
| SCHEMBL8589920 | 0.76 | TSHR (0.48) | TSHRALDH1A1PTPN1MAPK1KCNN4 | |
| SCHEMBL14768736 | 0.76 | TSHR (0.48) | TSHRALDH1A1PTPN1MAPK1KCNN4 | |
| SCHEMBL5663879 | 0.74 | ALDH1A1 (0.46) | TSHRALDH1A1PTPN1MAPK1KCNN4 | |
| SCHEMBL10268267 | 0.72 | ALDH1A1 (0.44) | TSHRALDH1A1PTPN1MAPK1KCNN4 | |
| SCHEMBL20815738 | 0.72 | ALDH1A1 (0.44) | TSHRALDH1A1PTPN1MAPK1KCNN4 | |
| SCHEMBL2938708 | 0.72 | ALDH1A1 (0.50) | TSHRALDH1A1PTPN1MAPK1KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1183075-C | Benzene derivative and its prepn. method | �����ɷ� | 2005-01-05 | — | — | CN | claimed |
| US-6231785-B1 | USEFUL FOR LIQUID CRYSTALLINE MATERIALS | CHISSO CORPORATION (JP) | 2001-05-15 | — | — | US | claimed |
| CN-1255475-A | Benzene derivative and its prepn. method | CHISSO CORP (JP) | 2000-06-07 | — | — | CN | claimed |
| JP-10017544-A | — | — | None | — | — | JP | disclosed |
| CN-110240587-B | Aryl difluoro benzyl ether compounds, preparation method and application | 中国科学院上海药物研究所 | 2022-01-04 | — | — | CN | disclosed |
| US-20130004455-A1 | POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-01-03 | — | — | US | disclosed |
| EP-2248872-A2 | Liquid crystalline medium | Merck Patent GmbH (DE) | 2010-11-10 | — | — | EP | disclosed |
| CN-101360513-A | Biodegradable and thermosensitive poly(organophosphazene) hydrogel, preparation method thereof and use thereof | KOREA INST SCI & TECH (KR) | 2009-02-04 | — | — | CN | disclosed |
| EP-1908813-A1 | Liquid crystalline medium | Merck Patent GmbH (DE) | 2008-04-09 | — | — | EP | disclosed |
| EP-1908811-A1 | Liquid crystalline medium | Merck Patent GmbH (DE) | 2008-04-09 | — | — | EP | disclosed |
| US-7326447-B2 | Benzochromene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-02-05 | — | — | US | disclosed |
| CN-1183075-C | Benzene derivative and its prepn. method | �����ɷ� | 2005-01-05 | — | — | CN | disclosed |
| JP-2003261478-A | METHOD FOR PRODUCING DIFLUOROBENZYL BROMIDE DERIVATIVE AND DIFLUOROBENZYL ETHER DERIVATIVE | SEIMI CHEM CO LTD | 2003-09-16 | — | — | JP | disclosed |
| US-6231785-B1 | USEFUL FOR LIQUID CRYSTALLINE MATERIALS | CHISSO CORPORATION (JP) | 2001-05-15 | — | — | US | disclosed |
| US-6231785-B1 | USEFUL FOR LIQUID CRYSTALLINE MATERIALS | CHISSO CORPORATION (JP) | 2001-05-15 | — | — | US | disclosed |
| CN-1255475-A | Benzene derivative and its prepn. method | CHISSO CORP (JP) | 2000-06-07 | — | — | CN | disclosed |
| CN-1255475-A | Benzene derivative and its prepn. method | CHISSO CORP (JP) | 2000-06-07 | — | — | CN | disclosed |
| JP-2000095715-A | BENZENE DERIVATIVE AND ITS PRODUCTION | CHISSO CORP | 2000-04-04 | — | — | JP | disclosed |
| JP-H1017544-A | THION-O-ESTER DERIVATIVE AND ITS PRODUCTION | CHISSO CORP | 1998-01-20 | — | — | JP | disclosed |
| US-5651919-A | Benzyl ether derivative and composition containing the same | CITIZEN WATCH CO., LTD. (JP) | 1997-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130004455-A1 | POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS | PHOSPHO1, PGLS, PHYKPL | TSHR 4580/4885ALDH1A1 2323/4885PTPN1 1405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.