Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | SORD | Q00796 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31008661 | 1.00 | P2RX7 (0.37) | P2RX7LMNATDP1NAMPTHSP90AA1 | |
| SCHEMBL4249241 | 0.81 | RECQL (0.39) | P2RX7HSP90AA1ALDH1A1KMT2ANPC1 | |
| SCHEMBL28596505 | 0.81 | P2RX7 (0.39) | P2RX7LMNATDP1NAMPTHSP90AA1 | |
| SCHEMBL497367 | 0.76 | LMNA (0.60) | LMNATDP1ALDH1A1KMT2ANPC1 | |
| SCHEMBL16399930 | 0.74 | — | — | |
| SCHEMBL1650881 | 0.74 | — | — | |
| SCHEMBL29925045 | 0.74 | KMT2A (0.39) | LMNAALDH1A1KMT2ARAB9AHTT | |
| SCHEMBL28629862 | 0.74 | KMT2A (0.63) | LMNATDP1ALDH1A1KMT2ANPC1 | |
| SCHEMBL29924865 | 0.74 | KMT2A (0.63) | LMNATDP1ALDH1A1KMT2ANPC1 | |
| SCHEMBL30365920 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912382-A | Light high-aluminum heat-insulation refractory brick and preparation method thereof | 唐山市凯伦保温材料有限公司 | 2022-01-11 | — | — | CN | disclosed |