Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22452527 | 0.85 | SERPINE1 (0.57) | EPHX2PGRCYP2C9NPC1CA1 | |
| SCHEMBL22453497 | 0.85 | SERPINE1 (0.57) | EPHX2PGRCYP2C9NPC1CA1 | |
| SCHEMBL22452577 | 0.83 | HIF1A (0.51) | EPHX2PGRCYP2C9NPC1CA1 | |
| SCHEMBL22453221 | 0.83 | HIF1A (0.51) | EPHX2PGRCYP2C9NPC1CA1 | |
| SCHEMBL22453626 | 0.81 | SERPINE1 (0.65) | EPHX2PGRCYP2C9NPC1CA1 | |
| SCHEMBL22452488 | 0.80 | SERPINE1 (0.64) | EPHX2PGRCYP2C9NPC1CA1 | |
| SCHEMBL22453766 | 0.78 | HPGD (0.56) | EPHX2PGRCYP2C9NPC1CA1 | |
| SCHEMBL28695220 | 0.77 | EPHX2 (0.43) | EPHX2PGRNPC1CA1CA2 | |
| SCHEMBL22453751 | 0.77 | HPGD (0.55) | EPHX2NPC1CA1CA2CA9 | |
| SCHEMBL22452806 | 0.76 | HIF1A (0.59) | EPHX2PGRCYP2C9NPC1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113811300-A | Novel small molecule inhibitors of TEAD transcription factor | 总医院公司 | 2021-12-17 | — | — | CN | disclosed |