Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22453449 | 0.84 | HIF1A (0.51) | EPHX2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL22453772 | 0.81 | MAPT (0.48) | EPHX2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL22445211 | 0.78 | EPHX2 (0.62) | EPHX2MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL28676301 | 0.77 | EPHX2 (0.54) | EPHX2MEN1KMT2ANPC1CA1 | |
| SCHEMBL22452967 | 0.74 | NPC1 (0.75) | EPHX2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL22452764 | 0.74 | KMT2A (0.48) | EPHX2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL22452708 | 0.72 | EPHX2 (0.41) | EPHX2MEN1KMT2AGAANPC1 | |
| SCHEMBL22453464 | 0.71 | POLB (0.58) | EPHX2KMT2AALDH1A1PKMNPC1 | |
| SCHEMBL22453102 | 0.70 | EPHX2 (0.49) | EPHX2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL22815320 | 0.70 | EPHX2 (0.57) | EPHX2MEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113811300-A | Novel small molecule inhibitors of TEAD transcription factor | 总医院公司 | 2021-12-17 | — | — | CN | disclosed |