Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 7/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 8/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 8/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670701 | 0.85 | DRD2 (0.53) | PRMT5WDR77DRD2 | |
| SCHEMBL28673307 | 0.83 | PRMT5 (0.43) | HDAC4NAMPTPRMT5WDR77KDM4E | |
| SCHEMBL28673309 | 0.83 | PRMT5 (0.43) | HDAC4NAMPTPRMT5WDR77KDM4E | |
| SCHEMBL28676326 | 0.80 | NAMPT (0.44) | NAMPT | |
| SCHEMBL28928596 | 0.79 | DRD2 (0.44) | PRMT5WDR77DRD2 | |
| SCHEMBL28654077 | 0.79 | HDAC4 (0.50) | HDAC4NAMPTPRMT5WDR77DRD2 | |
| SCHEMBL29758937 | 0.79 | HDAC4 (0.50) | HDAC4NAMPTPRMT5WDR77DRD2 | |
| SCHEMBL18215074 | 0.79 | HDAC4 (0.50) | HDAC4NAMPTPRMT5WDR77DRD2 | |
| SCHEMBL18205172 | 0.75 | HDAC4 (0.52) | HDAC4NAMPTPRMT5WDR77KDM4E | |
| SCHEMBL18212476 | 0.75 | NAMPT (0.49) | HDAC4NAMPTPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735088-B | Histone deacetylase inhibitors, compositions and methods of use thereof | CHDI基金会股份有限公司 | 2021-11-02 | — | — | CN | disclosed |