Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22145309 | 0.88 | PYCR1 (0.43) | MEN1KMT2APKMRAB9ANPC1 | |
| SCHEMBL2642550 | 0.82 | ERCC1 (0.54) | MEN1KMT2APKMRAB9APOLQ | |
| SCHEMBL16929973 | 0.80 | KDM4E (0.41) | MEN1KMT2ARAB9ANPC1KDM4E | |
| SCHEMBL19030893 | 0.79 | POLQ (0.43) | MEN1KMT2APKMRAB9APOLQ | |
| SCHEMBL29958566 | 0.78 | MAPT (0.43) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL4635493 | 0.78 | MAPT (0.43) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL13032640 | 0.78 | TAAR1 (0.43) | MEN1KMT2APOLQALDH1A1TDP1 | |
| SCHEMBL28684824 | 0.76 | NOS3 (0.40) | MEN1KMT2ANOS3NOS1NOS2 | |
| SCHEMBL31053255 | 0.76 | GAA (0.49) | MEN1KMT2APKMRAB9AKDM4E | |
| SCHEMBL7886929 | 0.76 | GAA (0.49) | MEN1KMT2APKMRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912597-B | ROR gamma inhibitor, preparation method and medical application thereof | 赛诺哈勃药业（成都）有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-113912597-A | ROR gamma inhibitor, preparation method and medical application thereof | 赛诺哈勃药业（成都）有限公司 | 2022-01-11 | — | — | CN | disclosed |