SCHEMBL28677174

SCHEMBL28677174

NC(=O)c1cccnc1-c1ccccc1-c1ccccc1N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.45
CSNK1A1 P48729 1/20 0.44
TYRO3 Q06418 1/20 0.44
DYRK1B Q9Y463 1/20 0.44
BTK Q06187 1/20 0.43
KDM4E B2RXH2 3/20 0.43
TDP1 Q9NUW8 1/20 0.43
BRD4 O60885 1/20 0.42
PTPRC P08575 2/20 0.42
CTSL P07711 1/20 0.42
CTSS P25774 1/20 0.42
PTPN13 Q12923 1/20 0.42
BCAT2 O15382 1/20 0.42
MKNK1 Q9BUB5 1/20 0.42
MKNK2 Q9HBH9 1/20 0.42
NAPRT Q6XQN6 1/20 0.41
GRM5 P41594 1/20 0.41
ALDH1A1 P00352 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15548944 0.83 BCAT2 (0.61) PARP1CSNK1A1TYRO3DYRK1BKDM4E
SCHEMBL29950470 0.81 KDM4E (0.65) KDM4ETDP1PTPRCCTSLCTSS
SCHEMBL6616370 0.81 KDM4E (0.53) PARP1CSNK1A1TYRO3DYRK1BKDM4E
SCHEMBL28035470 0.79 CSNK1A1 (0.49) PARP1CSNK1A1TYRO3DYRK1BKDM4E
SCHEMBL28062810 0.79 SMN1; SMN2 (0.55) PARP1CSNK1A1TYRO3DYRK1BKDM4E
SCHEMBL2330384 0.79 KMT2A (0.50) PARP1CSNK1A1TYRO3DYRK1BKDM4E
SCHEMBL4782635 0.79 MAPT (0.55) PARP1CSNK1A1TYRO3DYRK1BKDM4E
SCHEMBL4186883 0.79 KDM4E (0.65) PARP1CSNK1A1TYRO3DYRK1BKDM4E
SCHEMBL1685834 0.78 TDP1 (0.52) PARP1CSNK1A1TYRO3DYRK1BTDP1
SCHEMBL29516168 0.78 TDP1 (0.52) PARP1CSNK1A1TYRO3DYRK1BTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114573811-A Imide slurry, synthesis method thereof and composition containing imide slurry 宁波博雅聚力新材料科技有限公司 2022-06-03 CN disclosed
CN-113881225-A Imide film and synthetic method thereof 宁波博雅聚力新材料科技有限公司 2022-01-04 CN disclosed