Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28678751 | 0.84 | SRD5A2 (0.52) | TSHRMAPK1LMNAMIFGSK3B | |
| SCHEMBL3459152 | 0.76 | CYP2A6 (0.44) | TSHRMAPK1CYP2A6GSK3BIDO1 | |
| SCHEMBL4701959 | 0.75 | CYP19A1 (0.41) | MEN1KMT2ATSHRMAPK1HIF1A | |
| SCHEMBL10588674 | 0.72 | KCNN4 (0.41) | TSHRMAPK1KIF11 | |
| SCHEMBL16795606 | 0.72 | MEN1 (0.37) | MEN1KMT2ATSHRMAPK1HIF1A | |
| SCHEMBL15759500 | 0.72 | KMT2A (0.58) | MEN1KMT2ATSHRMAPK1HIF1A | |
| SCHEMBL22615031 | 0.70 | MEN1 (0.40) | MEN1KMT2ATSHRMAPK1HIF1A | |
| SCHEMBL95552 | 0.69 | MEN1 (0.62) | MEN1KMT2ATSHRMAPK1HIF1A | |
| SCHEMBL28693893 | 0.69 | KIF11 (0.47) | TSHRCYP2A6GSK3BCYP19A1KIF11 | |
| SCHEMBL11209461 | 0.68 | KMT2A (0.54) | MEN1KMT2ATSHRMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113801005-A | Preparation method of alpha-bromoacetophenone compound | 浙江师范大学 | 2021-12-17 | — | — | CN | disclosed |
| CN-113800998-A | Preparation method of (2-bromoethynyl) benzene compound | 浙江师范大学 | 2021-12-17 | — | — | CN | disclosed |