SCHEMBL3459152

SCHEMBL3459152

BrCC(Br)(Br)c1ccc(Br)cc1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.44
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA5A P35218 1/20 0.37
CA9 Q16790 1/20 0.37
GSK3B P49841 2/20 0.36
ALDH1A1 P00352 4/20 0.35
ALOX15 P16050 2/20 0.35
MAPK1 P28482 2/20 0.35
OGG1 O15527 1/20 0.34
HTR2A P28223 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
IDO1 P14902 2/20 0.32
PLCG1 P19174 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PYCR1 P32322 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9440148 0.80 CYP2A6 (0.47) CYP2A6CA1CA2CA5ACA9
SCHEMBL10588674 0.74 KCNN4 (0.41) ALDH1A1MAPK1TAAR1TDP1TSHR
SCHEMBL19510596 0.74 CA1 (0.43) CYP2A6CA1CA2CA5ACA9
SCHEMBL12807003 0.70 CA1 (0.41) CYP2A6CA1CA2CA5ACA9
SCHEMBL3459530 0.70 CA1 (0.44) CA1CA2CA5ACA9ALDH1A1
SCHEMBL440244 0.69 CYP2A6 (0.57) CYP2A6CA1CA2CA5ACA9
SCHEMBL11051817 0.69 CYP2A6 (0.57) CYP2A6CA1CA2CA5ACA9
SCHEMBL11257478 0.69 CYP2A6 (0.35) CYP2A6CA1CA2CA5ACA9
SCHEMBL452554 0.67 ALDH1A1 (0.40) CYP2A6CA1CA2CA5ACA9
SCHEMBL25278922 0.67 CYP2A6 (0.44) CYP2A6CA1CA2CA5ACA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113800998-A Preparation method of (2-bromoethynyl) benzene compound 浙江师范大学 2021-12-17 CN disclosed
EP-2241546-B1 PROCESS FOR PRODUCTION OF BENZALDEHYDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2017-10-04 EP disclosed
US-8937200-B2 Method for producing 2-(aryloxymethyl) benzaldehyde compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-20 US disclosed
US-20140221695-A1 METHOD FOR PRODUCING 2-(ARYLOXYMETHYL) BENZALDEHYDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-08-07 US disclosed
EP-2727902-A1 METHOD FOR PRODUCING 2-(ARYLOXYMETHYL)BENZALDEHYDE COMPOUND Sumitomo Chemical Company Limited (JP) 2014-05-07 EP disclosed
US-8258349-B2 Process for production of benzaldehyde compound SUITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-09-04 US disclosed
US-20100292513-A1 PROCESS FOR PRODUCTION OF BENZALDEHYDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-18 US disclosed
EP-2241546-A1 PROCESS FOR PRODUCTION OF BENZALDEHYDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292513-A1 PROCESS FOR PRODUCTION OF BENZALDEHYDE COMPOUND CBR3, ADH5, ALDH1A1 CYP2A6 158/4885CA1 2100/4885CA2 1887/4885
US-20140221695-A1 METHOD FOR PRODUCING 2-(ARYLOXYMETHYL) BENZALDEHYDE COMPOUND AOX1, BBOX1, B2M CYP2A6 48/4885CA1 995/4885CA2 661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.