SCHEMBL2867779

SCHEMBL2867779

C=C(C)CCCC=C(C)COCc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LSS P48449 2/20 0.40
FNTA P49354 1/20 0.40
FNTB P49356 1/20 0.40
TSHR P16473 1/20 0.39
MAPT P10636 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HTT P42858 1/20 0.35
FAAH O00519 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NPC1 O15118 1/20 0.34
TRPV1 Q8NER1 1/20 0.33
ICMT O60725 1/20 0.33
GRM5 P41594 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2867777 1.00 LSS (0.40) LSSFNTAFNTBTSHRMAPT
SCHEMBL29319606 0.83 HTT (0.36) LSSMAPTHTTFAAH
SCHEMBL10000151 0.81 TSHR (0.42) LSSFNTAFNTBTSHRMAPT
SCHEMBL19850432 0.79 FNTA (0.46) LSSFNTAFNTBTSHRMAPT
SCHEMBL2865999 0.79 GPR174 (0.40) L3MBTL1
SCHEMBL2865998 0.79 GPR174 (0.40) L3MBTL1
SCHEMBL2870332 0.78 LSS (0.49) LSSFNTAFNTBTSHRALDH1A1
SCHEMBL10000088 0.78 LSS (0.46) LSSFNTAFNTBTSHRMAPT
SCHEMBL2870331 0.78 LSS (0.49) LSSFNTAFNTBTSHRALDH1A1
SCHEMBL10000083 0.77 LSS (0.43) LSSFNTAFNTBTSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7728180-B2 Method for producing ethers KURARAY CO., LTD. (JP) 2010-06-01 US disclosed
US-20080262272-A1 Method For Producing Ethers KURARAY CO., LTD. (JP) 2008-10-23 US disclosed
CN-1972888-A Method for producing ethers KURARAY CO (JP) 2007-05-30 CN disclosed
EP-1760061-A1 METHOD FOR PRODUCING ETHERS KURARAY CO., LTD. (JP) 2007-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080262272-A1 Method For Producing Ethers TELO2, PDS5A, TERT LSS 1302/4885FNTA 4026/4885FNTB 3784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.