SCHEMBL2865998

SCHEMBL2865998

C=C(C)CCC/C=C(\C)COc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR174 Q9BXC1 1/20 0.40
MAOB P27338 4/20 0.40
AOC3 Q16853 3/20 0.40
MEN1 O00255 1/20 0.40
ALPL P05186 1/20 0.40
ALPI P09923 1/20 0.40
ALPG P10696 1/20 0.40
KMT2A Q03164 1/20 0.40
ALOX15 P16050 1/20 0.40
AOC2 O75106 2/20 0.36
MAOA P21397 2/20 0.36
DAO P14920 1/20 0.36
KCNA3 P22001 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
BTN3A1 O00481 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2865999 1.00 GPR174 (0.40) GPR174MAOBAOC3MEN1ALPL
SCHEMBL2867777 0.79 LSS (0.40) L3MBTL1
SCHEMBL2867779 0.79 LSS (0.40) L3MBTL1
SCHEMBL2868632 0.77 LSS (0.40) GPR174AOC3ALOX15KCNA3L3MBTL1
SCHEMBL2868634 0.77 LSS (0.40) GPR174AOC3ALOX15KCNA3L3MBTL1
SCHEMBL1486040 0.74 GPR174 (0.62) GPR174MAOBAOC3MEN1ALPL
SCHEMBL7428825 0.74 KCNA3 (0.59) KCNA3L3MBTL1
SCHEMBL2866504 0.74 LMNA (0.39) MAOBAOC3ALOX15AOC2MAOA
SCHEMBL2866505 0.74 LMNA (0.39) MAOBAOC3ALOX15AOC2MAOA
SCHEMBL1269879 0.73 KMT2A (0.31) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7728180-B2 Method for producing ethers KURARAY CO., LTD. (JP) 2010-06-01 US disclosed
US-20080262272-A1 Method For Producing Ethers KURARAY CO., LTD. (JP) 2008-10-23 US disclosed
EP-1760061-A1 METHOD FOR PRODUCING ETHERS KURARAY CO., LTD. (JP) 2007-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080262272-A1 Method For Producing Ethers TELO2, PDS5A, TERT GPR174 3363/4885MAOB 4049/4885AOC3 836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.