SCHEMBL2867790

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4788120	0.79	LRRK2 (0.56)	FBP1MAPTKDM4EMEN1CYP1A2
	SCHEMBL2862227	0.76	ADORA2A (0.49)	MAPTKDM4EMEN1KMT2AALDH1A1
	SCHEMBL30799435	0.75	MAPT (0.50)	FBP1MAPTKDM4EMEN1CYP1A2
	SCHEMBL27143397	0.75	MAPT (0.50)	FBP1MAPTKDM4EMEN1CYP1A2
	SCHEMBL2995599	0.75	FBP1 (0.46)	FBP1MAPTKDM4EMEN1CYP1A2
	SCHEMBL2860859	0.75	MAP2K7 (0.59)	MAPTMEN1KMT2AMAPK1HPGD
	SCHEMBL8529578	0.74	PDE10A (0.47)	FBP1MAPTKDM4EMEN1BLM
	SCHEMBL23722436	0.74	MAP2K7 (0.67)	FBP1AURKAAURKB
	SCHEMBL2858316	0.74	MAP2K4 (0.52)	FBP1MAPTKDM4EMAPK1TDP1
	SCHEMBL17829707	0.74	ALDH1A1 (0.49)	FBP1MAPTKDM4EMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.