SCHEMBL2862227

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2858263	0.79	HTR7 (0.44)	ADORA2AHTR7AURKATDO2MAP2K4
	SCHEMBL2859154	0.78	CHUK (0.46)	ADORA2AHTR7TDO2MAP2K4NOTUM
	SCHEMBL2861121	0.78	ADORA2A (0.43)	ADORA2AHTR7AURKATDO2MAP2K4
	SCHEMBL2858316	0.77	MAP2K4 (0.52)	ADORA2AHTR7TDO2MAP2K4NOTUM
	SCHEMBL2859865	0.76	MAP2K4 (0.51)	ADORA2AHTR7AURKATDO2MAP2K4
	SCHEMBL2867790	0.76	FBP1 (0.55)	HTR7AURKATDO2MAP2K4NOTUM
	SCHEMBL4788625	0.76	IMPDH2 (0.55)	AURKAMAP4K4CSF1RFGFR1PDGFRA
	SCHEMBL2860957	0.76	AURKA (0.66)	ADORA2AHTR7AURKATDO2MAP2K4
	SCHEMBL27558549	0.75	MAP2K4 (0.41)	ADORA2AHTR7TDO2MAP2K4NOTUM
	SCHEMBL14516332	0.74	AURKA (0.59)	ADORA2AHTR7AURKATDO2MAP2K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.