Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | KIF20A | O95235 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27908791 | 0.88 | HTR2A (0.35) | HTR2AHTR2BHTR6HTR2CMTNR1A | |
| SCHEMBL27369292 | 0.83 | GPR84 (0.44) | HTR2AHTR2BHTR2CMAPTMEN1 | |
| SCHEMBL27891882 | 0.82 | HTR2A (0.37) | HTR2AMAPTMEN1KMT2ATDP1 | |
| SCHEMBL27524231 | 0.82 | NR4A2 (0.46) | HTR2AHTR2BHTR2C | |
| SCHEMBL27906752 | 0.82 | FFAR1 (0.43) | HTR2AHTR2BHTR6HTR2CHTR1A | |
| SCHEMBL27965809 | 0.82 | CYP2A6 (0.35) | HTR2AHTR2BHTR2CCLK1 | |
| SCHEMBL27771264 | 0.82 | HTR2A (0.44) | HTR2AHTR2BHTR6HTR2CHTR1A | |
| SCHEMBL27472077 | 0.81 | HTR2A (0.51) | HTR2AHTR1AMAPTMEN1KMT2A | |
| SCHEMBL27580249 | 0.81 | MEN1 (0.36) | HTR2AHTR6MTNR1AMTNR1BMAPT | |
| SCHEMBL25990382 | 0.81 | HTR2A (0.53) | HTR2AHTR2BHTR6HTR2CMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748840-B | Synthetic method of 2-substituted indole derivative | 中国医学科学院药物研究所 | 2021-12-07 | — | — | CN | disclosed |