Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 5/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.30 |
| ▸ | MELK | Q14680 | 1/20 | 0.30 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27369292 | 0.84 | GPR84 (0.44) | CYP2A6HTR2AHTR2CHTR2BGPR84 | |
| SCHEMBL27771264 | 0.83 | HTR2A (0.44) | CYP2A6HTR2AHTR2CHTR2BNR4A2 | |
| SCHEMBL27524231 | 0.83 | NR4A2 (0.46) | CYP2A6HTR2AHTR2CHTR2BGPR84 | |
| SCHEMBL27906752 | 0.83 | FFAR1 (0.43) | CYP2A6HTR2AHTR2CHTR2BGPR84 | |
| SCHEMBL28678155 | 0.82 | HTR2A (0.45) | HTR2AHTR2CHTR2BCLK1 | |
| SCHEMBL28293156 | 0.81 | ALDH1A1 (0.39) | NR4A2 | |
| SCHEMBL27908791 | 0.81 | HTR2A (0.35) | CYP2A6HTR2AHTR2CHTR2BGPR84 | |
| SCHEMBL28291599 | 0.80 | POLB (0.37) | HTR2AHTR2CHTR2BGPR84FFAR1 | |
| SCHEMBL28818816 | 0.80 | SLC6A4 (0.39) | CYP2A6HTR2AGPR84FFAR1 | |
| SCHEMBL27704230 | 0.79 | BACE1 (0.40) | GPR84FFAR1CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103957910-A | Compounds and methods for enhancing innate immune responses | GLAXOSMITHKLINE LLC | 2014-07-30 | — | — | CN | disclosed |