Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 7/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27369292 | 0.84 | GPR84 (0.44) | FFAR1GPR84HTR2AHTR2CHTR2B | |
| SCHEMBL27908791 | 0.83 | HTR2A (0.35) | FFAR1GPR84HTR2AHTR2CHTR2B | |
| SCHEMBL27771264 | 0.83 | HTR2A (0.44) | HTR2AHTR2CHTR2BCYP2A6HTR1A | |
| SCHEMBL27524231 | 0.83 | NR4A2 (0.46) | FFAR1GPR84HTR2AHTR2CHTR2B | |
| SCHEMBL27965809 | 0.83 | CYP2A6 (0.35) | FFAR1GPR84HTR2AHTR2CHTR2B | |
| SCHEMBL28678155 | 0.82 | HTR2A (0.45) | HTR2AHTR2CHTR2BHTR1AHTR7 | |
| SCHEMBL27472999 | 0.82 | GPR84 (0.33) | GPR84 | |
| SCHEMBL27694363 | 0.81 | GPR84 (0.32) | GPR84 | |
| SCHEMBL28818816 | 0.80 | SLC6A4 (0.39) | FFAR1GPR84HTR2ASLC6A4CYP2A6 | |
| SCHEMBL28291599 | 0.80 | POLB (0.37) | FFAR1GPR84HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105601555-B | A method of preparing nitroindole derivative | 苏州大学 | 2018-07-31 | — | — | CN | disclosed |
| CN-102918042-A | 8-methyl-1-phenyl-imidazo [1,5-a ] pyrazine compounds | MSD OSS BV | 2013-02-06 | — | — | CN | disclosed |