Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | GLA | P06280 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28352180 | 0.81 | ALDH1A1 (0.61) | KDM4EGLAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28883171 | 0.81 | KDM4E (0.61) | KDM4EGLAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28351868 | 0.81 | KDM4E (0.61) | KDM4EGLAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL11245977 | 0.78 | AKR1B1 (0.71) | KDM4EGLAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28674785 | 0.77 | KDM4E (0.56) | KDM4EGLAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28661256 | 0.77 | ALPG (0.57) | KDM4EGLAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL2427657 | 0.76 | KDM4E (1.00) | KDM4EGLAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28669952 | 0.76 | ALDH1A1 (0.68) | KDM4EGLAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL11267010 | 0.75 | CTDSP1 (0.55) | KDM4EGLAALDH1A1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30228536 | 0.75 | KDM4E (0.96) | KDM4EGLAALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110252351-B | Application of copper catalyst in catalyzing reaction of 1-pyridyl indole compound and tert-butyl nitrite | 苏州大学 | 2021-12-10 | — | — | CN | disclosed |