Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | CASP1 | P29466 | 2/20 | 0.51 |
| ▸ | CASP7 | P55210 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | PTAFR | P25105 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276381 | 0.83 | MEN1 (0.59) | CTDSP1KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL11276307 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1GAASMN1; SMN2HPGD | |
| SCHEMBL11263329 | 0.80 | ALPG (0.58) | CTDSP1KDM4EALDH1A1GAAGLA | |
| SCHEMBL11269694 | 0.79 | ALPG (0.69) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL11245977 | 0.78 | AKR1B1 (0.71) | CTDSP1KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL11089921 | 0.76 | PTAFR (0.46) | CTDSP1KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL28678221 | 0.75 | KDM4E (0.61) | CTDSP1KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28351868 | 0.75 | KDM4E (0.61) | CTDSP1KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28883171 | 0.75 | KDM4E (0.61) | CTDSP1KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28352180 | 0.75 | ALDH1A1 (0.61) | CTDSP1KDM4EALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348396-A | Substituted 11-oxo-11H-pyrido[2,1-b]quinazolines and method of inhibiting allergic reactions with them | HOFFMANN-LA ROCHE INC. (US) | 1982-09-07 | — | — | US | disclosed |