Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31382710 | 1.00 | TAS1R3 (0.47) | TAS1R3TAS1R1RAB9ANPC1CASP1 | |
| SCHEMBL29368169 | 1.00 | TAS1R3 (0.47) | TAS1R3TAS1R1RAB9ANPC1CASP1 | |
| SCHEMBL22441250 | 0.88 | TAS1R3 (0.52) | TAS1R3TAS1R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22441253 | 0.88 | TAS1R3 (0.52) | TAS1R3TAS1R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22458123 | 0.86 | RAB9A (0.45) | RAB9ANPC1CASP1SMN1; SMN2MTNR1B | |
| SCHEMBL29368864 | 0.83 | TAS1R3 (0.61) | TAS1R3TAS1R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22441334 | 0.83 | TAS1R3 (0.55) | TAS1R3TAS1R1SMN1; SMN2CTSKHPGD | |
| SCHEMBL29368573 | 0.83 | TAS1R3 (0.55) | TAS1R3TAS1R1SMN1; SMN2CTSKHPGD | |
| SCHEMBL22441335 | 0.83 | TAS1R3 (0.55) | TAS1R3TAS1R1SMN1; SMN2CTSKHPGD | |
| SCHEMBL27175282 | 0.83 | TAS1R3 (0.55) | TAS1R3TAS1R1CTSKMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008024-A | Compounds having iron death inducing activity and methods of using the same | 费罗治疗公司 | 2022-02-01 | — | — | CN | disclosed |