Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | FPR1 | P21462 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22441250 | 1.00 | TAS1R3 (0.52) | TAS1R3TAS1R1MEN1KMT2AHIF1A | |
| SCHEMBL29368864 | 0.90 | TAS1R3 (0.61) | TAS1R3TAS1R1MEN1KMT2ANPC1 | |
| SCHEMBL29368169 | 0.88 | TAS1R3 (0.47) | TAS1R3TAS1R1MEN1KMT2AMAPT | |
| SCHEMBL28678227 | 0.88 | TAS1R3 (0.47) | TAS1R3TAS1R1MEN1KMT2AMAPT | |
| SCHEMBL31382710 | 0.88 | TAS1R3 (0.47) | TAS1R3TAS1R1MEN1KMT2AMAPT | |
| SCHEMBL22441335 | 0.87 | TAS1R3 (0.55) | TAS1R3TAS1R1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22441334 | 0.87 | TAS1R3 (0.55) | TAS1R3TAS1R1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29368573 | 0.87 | TAS1R3 (0.55) | TAS1R3TAS1R1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27175282 | 0.87 | TAS1R3 (0.55) | TAS1R3TAS1R1MEN1KMT2ACTSK | |
| SCHEMBL27175279 | 0.87 | TAS1R3 (0.55) | TAS1R3TAS1R1MEN1KMT2ACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002280-A1 | COMPOUNDS AND METHODS OF USE | FERRO THERAPEUTICS INC (US) | 2022-01-06 | — | — | US | disclosed |
| US-11040964-B2 | Compounds and methods of use | Ferro Therapeutics, Inc. (US) | 2021-06-22 | — | — | US | disclosed |
| US-20200299283-A1 | COMPOUNDS AND METHODS OF USE | BRIDGEBIO PHARMA, INC. | 2020-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002280-A1 | COMPOUNDS AND METHODS OF USE | AIFM2, GPX4, GPX1 | TAS1R3 3730/4885TAS1R1 3650/4885MEN1 1772/4885 |
| US-20200299283-A1 | COMPOUNDS AND METHODS OF USE | AIFM2, GPX4, GPX1 | TAS1R3 3730/4885TAS1R1 3650/4885MEN1 1772/4885 |
| US-11040964-B2 | Compounds and methods of use | AIFM2, GPX4, GPX1 | TAS1R3 3730/4885TAS1R1 3650/4885MEN1 1772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.