SCHEMBL28678472

SCHEMBL28678472

COc1cc[c]c(CCl)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
GFER P55789 1/20 0.37
DYRK1A Q13627 1/20 0.35
CA1 P00915 3/20 0.34
CA2 P00918 3/20 0.34
CA7 P43166 3/20 0.34
CA9 Q16790 3/20 0.34
CA12 O43570 2/20 0.34
CA14 Q9ULX7 2/20 0.34
MAPT P10636 4/20 0.34
LMNA P02545 2/20 0.34
RAB9A P51151 2/20 0.34
MEN1 O00255 1/20 0.34
MITF O75030 1/20 0.34
KMT2A Q03164 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ACHE P22303 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2A6 P11509 1/20 0.33
KDM4E B2RXH2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8917172 0.85 TAAR1 (0.36) ALDH1A1GFERCA1CA2CA7
SCHEMBL457740 0.82 CA1 (0.35) ALDH1A1GFERCA1CA2CA7
SCHEMBL28725283 0.80 IDO1 (0.35) ALDH1A1CA1CA2CA7CA9
SCHEMBL7390049 0.80 ABCB11 (0.36) ALDH1A1DYRK1ACA1CA2CA7
SCHEMBL8627266 0.80 IDO1 (0.42) ALDH1A1GFERCA1CA2CA7
SCHEMBL3918671 0.80 TAAR1 (0.39) ALDH1A1CA1CA2CA7CA9
SCHEMBL7400862 0.78 DRD2 (0.35) CA1CA2CA7CA9CA12
SCHEMBL18706270 0.78 SLC6A4 (0.40) ALDH1A1
SCHEMBL7386695 0.77 CYP2D6 (0.41) CA1CA2CA7CA9CA12
SCHEMBL7231639 0.77 CHRM2 (0.39) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113966326-A Water soluble adjuvants 大日本住友制药株式会社 2022-01-21 CN disclosed