Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.33 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.33 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053089 | 0.89 | HRH2 (0.37) | DRD2TAAR1SIGMAR1MAPTHRH3 | |
| SCHEMBL462206 | 0.87 | PTGS2 (0.42) | — | |
| SCHEMBL457740 | 0.84 | CA1 (0.35) | DRD2TAAR1SIGMAR1CA12CA1 | |
| SCHEMBL8917172 | 0.83 | TAAR1 (0.36) | TAAR1SIGMAR1ADRA1ACA12CA1 | |
| SCHEMBL10748671 | 0.83 | TAAR1 (0.49) | TAAR1ADRA1AHTR6MAPT | |
| SCHEMBL7386695 | 0.83 | CYP2D6 (0.41) | TAAR1CYP19A1SIGMAR1ADRA1ACA12 | |
| SCHEMBL8183757 | 0.81 | ALDH1A1 (0.36) | TAAR1 | |
| SCHEMBL7669645 | 0.81 | MAOB (0.44) | TAAR1CYP19A1SIGMAR1TUBB4ATUBB | |
| SCHEMBL6638432 | 0.80 | HTR2A (0.44) | HTR6 | |
| SCHEMBL7676584 | 0.80 | HTT (0.40) | DRD2TAAR1CYP19A1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1553900-A | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents | ��ʱ��ʩ����ҩ��˾ | 2004-12-08 | — | — | CN | disclosed |
| US-6156815-A | Acid-curable binder systems containing 1,2-disulfones | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-12-05 | — | — | US | disclosed |
| US-5985950-A | Acid-curable binder systems containing 1,2 disulfones | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-11-16 | — | — | US | disclosed |
| US-5717003-A | LATENT ACID CATALYST | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-02-10 | — | — | US | disclosed |
| EP-0707585-A1 | BICYCLIC TETRAHYDRO PYRAZOLOPYRIDINES | PFIZER INC. (US) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001980-A1 | BICYCLIC TETRAHYDRO PYRAZOLOPYRIDINES | PFIZER INC. (US) | 1995-01-19 | — | — | WO | disclosed |
| US-4980508-A | Oxidation of 1,2-disulonyhydrazine compound with concentrated nitric acid | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-12-25 | — | — | US | disclosed |
| US-4461726-A | Desulfurization of penicillins to prepare azetidinones | HOFFMANN-LA ROCHE INC. (US) | 1984-07-24 | — | — | US | disclosed |
| US-4195021-A | 1,3-Disubstituted 2-azetidinone antibitotics | ELI LILLY AND COMPANY (US) | 1980-03-25 | — | — | US | disclosed |
| EP-0001715-A2 | Azetidinone antibiotics and their pharmaceutical formulations and use | ELI LILLY AND COMPANY (US) | 1979-05-02 | — | — | EP | disclosed |