Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27416181 | 0.84 | POLB (0.54) | POLBTSHRALDH1A1L3MBTL1MEN1 | |
| SCHEMBL15438677 | 0.81 | NPC1 (0.46) | POLBTSHRALDH1A1L3MBTL1MEN1 | |
| SCHEMBL30338421 | 0.80 | POLB (0.61) | POLBTSHRALDH1A1L3MBTL1MEN1 | |
| SCHEMBL29093653 | 0.80 | POLB (0.61) | POLBTSHRALDH1A1L3MBTL1MEN1 | |
| SCHEMBL6360536 | 0.80 | POLB (0.61) | POLBTSHRALDH1A1L3MBTL1MEN1 | |
| SCHEMBL15361506 | 0.79 | ALDH1A1 (0.81) | POLBTSHRALDH1A1L3MBTL1MEN1 | |
| SCHEMBL28717787 | 0.78 | ALDH1A1 (1.00) | POLBTSHRALDH1A1L3MBTL1MEN1 | |
| SCHEMBL17937989 | 0.77 | ALDH1A1 (0.49) | POLBTSHRALDH1A1L3MBTL1MEN1 | |
| SCHEMBL24225368 | 0.77 | ELANE (0.49) | POLBTSHRALDH1A1L3MBTL1MEN1 | |
| SCHEMBL29012556 | 0.76 | L3MBTL1 (0.44) | POLBTSHRALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113968786-A | Process for preparing two methyl-substituted 2-oxo-3-cyclopentene-1-carboxylate compounds and dicarboxylate compounds for preparation | 信越化学工业株式会社 | 2022-01-25 | — | — | CN | disclosed |