Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 2/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6085867 | 0.81 | LOXL2 (0.50) | LOXL2TAAR1IDO1TDO2GABBR2 | |
| SCHEMBL4672668 | 0.79 | HRH1 (0.62) | LOXL2TAAR1HRH1 | |
| SCHEMBL22620835 | 0.79 | HRH1 (0.62) | LOXL2TAAR1HRH1 | |
| SCHEMBL5189954 | 0.79 | HRH1 (0.62) | LOXL2TAAR1HRH1 | |
| SCHEMBL11076863 | 0.79 | DPP4 (0.44) | LOXL2TAAR1IDO1TDO2GABBR2 | |
| SCHEMBL4618800 | 0.79 | HRH1 (0.62) | LOXL2TAAR1IDO1TDO2GABBR2 | |
| Hydrochloric Acid SCHEMBL9662256 | 0.77 | HRH1 (0.60) | LOXL2TAAR1IDO1TDO2HRH1 | |
| Hydrochloric Acid SCHEMBL7970943 | 0.77 | HRH1 (0.60) | LOXL2TAAR1HRH1 | |
| SCHEMBL7350168 | 0.76 | AOC3 (0.53) | TAAR1GABBR2GABBR1AOC3 | |
| SCHEMBL8350845 | 0.76 | AOC3 (0.53) | TAAR1GABBR2GABBR1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113582906-B | Difluoro benzphetamine compound and preparation method and application thereof | 郑州大学 | 2023-05-16 | — | — | CN | claimed |
| CN-113582906-A | Difluorophenyl ring propylamine compound and preparation method and application thereof | 郑州大学 | 2021-11-02 | — | — | CN | claimed |
| CN-113582906-B | Difluoro benzphetamine compound and preparation method and application thereof | 郑州大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-113582906-B | Difluoro benzphetamine compound and preparation method and application thereof | 郑州大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-109336829-B | Aryl formamide compound containing 1,2, 3-triazole structure and application thereof | 沈阳药科大学 | 2022-03-01 | — | — | CN | disclosed |