Sugi Predict

Sugi Predict / Compounds / SCHEMBL7350168

SCHEMBL7350168

SCHEMBL7350168

NCCC(O)c1ccc(F)cc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ AOC3 Q16853 1/20 0.53
▸ MEN1 O00255 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ GABBR2 O75899 1/20 0.46
▸ GABBR1 Q9UBS5 1/20 0.46
▸ TAAR1 Q96RJ0 3/20 0.43
▸ HTR3A P46098 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ NFKB1 P19838 1/20 0.43
▸ HIF1A Q16665 1/20 0.43
▸ KDM4E B2RXH2 2/20 0.43
▸ ALOX15 P16050 1/20 0.42
▸ APEX1 P27695 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8350845 1.00 AOC3 (0.53) AOC3MEN1KMT2AGABBR2GABBR1
SCHEMBL8355999 1.00 AOC3 (0.53) AOC3MEN1KMT2AGABBR2GABBR1
SCHEMBL15607723 0.89 AOC3 (0.52) AOC3MEN1KMT2AGABBR2GABBR1
SCHEMBL5093350 0.85 MEN1 (0.48) AOC3MEN1KMT2AGABBR2GABBR1
SCHEMBL31489731 0.84 AOC3 (0.50) AOC3MEN1KMT2AGABBR2GABBR1
SCHEMBL297244 0.82 TAAR1 (0.64) AOC3MEN1KMT2AGABBR2GABBR1
SCHEMBL295194 0.82 TAAR1 (0.64) AOC3MEN1KMT2AGABBR2GABBR1
SCHEMBL1239403 0.82 TAAR1 (0.64) AOC3MEN1KMT2AGABBR2GABBR1
SCHEMBL3823740 0.80 TAAR1 (0.68) MEN1KMT2ATAAR1HTR3ATSHR
Hydrochloric Acid SCHEMBL19666947 0.80 APEX1 (0.65) AOC3MEN1KMT2AGABBR2GABBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0972764-A1 Aminoalcohols and aminoketones as CNS active agents Universita Degli Studi di Firenze (IT) 2000-01-19 — — EP claimed
WO-2025076017-A1 CARBAMATES FOR USE AS SARM1 INHIBITORS GENENTECH, INC. (US) 2025-04-10 — — WO disclosed
US-20250074909-A1 AMINOTRIAZOLOPYRIDINES AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2025-03-06 — — US disclosed
WO-2025038930-A1 AZEPANE AND PYRROLIDINE COMPOUNDS AND USES THEREOF XENON PHARMACEUTICALS, INC. (CA) 2025-02-20 — — WO disclosed
US-12157733-B2 Aminotriazolopyridines as kinase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2024-12-03 — — US disclosed
EP-3743430-B1 AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2023-08-02 — — EP disclosed
EP-3743430-B1 AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2023-08-02 — — EP disclosed
CN-112262139-B Aminopyrrolotriazines as kinase inhibitors 百时美施贵宝公司 2023-07-25 — — CN disclosed
US-11618753-B2 Aminopyrrolotriazines as kinase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2023-04-04 — — US disclosed
US-20220315580-A1 AMINOTRIAZOLOPYRIDINES AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2022-10-06 — — US disclosed
WO-2019147782-A1 AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2019-08-01 — — WO disclosed
US-20170369444-A1 INHIBITORS OF HISTONE DEMETHYLASES EPITHERAPEUTICS APS (DK) 2017-12-28 — — US disclosed
EP-2758401-B1 AMINO-SUBSTITUTED IMIDAZOPYRIDAZINES BAYER IP GMBH (DE) 2017-05-31 — — EP disclosed
EP-3126345-A1 INHIBITORS OF HISTONE DEMETHYLASES Gilead Sciences, Inc. (US) 2017-02-08 — — EP disclosed
US-9499547-B2 Amino-substituted imidazopyridazines BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-11-22 — — US disclosed
WO-2015153498-A1 INHIBITORS OF HISTONE DEMETHYLASES EPITHERAPEUTICS, APS (DK) 2015-10-08 — — WO disclosed
US-20140296231-A1 AMINO-SUBSTITUTED IMIDAZOPYRIDAZINES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-10-02 — — US disclosed
EP-2758401-A1 AMINO-SUBSTITUTED IMIDAZOPYRIDAZINES Bayer Intellectual Property GmbH (DE) 2014-07-30 — — EP disclosed
WO-2013034570-A1 AMINO-SUBSTITUTED IMIDAZOPYRIDAZINES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-03-14 — — WO disclosed
EP-0972764-A1 Aminoalcohols and aminoketones as CNS active agents Universita Degli Studi di Firenze (IT) 2000-01-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170369444-A1 INHIBITORS OF HISTONE DEMETHYLASES KDM1B, KDM3A, KDM1A AOC3 1423/4885MEN1 3018/4885KMT2A 44/4885
US-20250074909-A1 AMINOTRIAZOLOPYRIDINES AS KINASE INHIBITORS RIPK1, RIPK3, RIPK4 AOC3 4571/4885MEN1 3964/4885KMT2A 1408/4885
US-20220315580-A1 AMINOTRIAZOLOPYRIDINES AS KINASE INHIBITORS RIPK1, RIPK3, RIPK4 AOC3 4571/4885MEN1 3964/4885KMT2A 1408/4885
US-20140296231-A1 AMINO-SUBSTITUTED IMIDAZOPYRIDAZINES VEGFA, CCND2, CCND1 AOC3 2865/4885MEN1 1149/4885KMT2A 1489/4885
US-12157733-B2 Aminotriazolopyridines as kinase inhibitors RIPK1, RIPK3, RIPK4 AOC3 4571/4885MEN1 3964/4885KMT2A 1408/4885
US-11618753-B2 Aminopyrrolotriazines as kinase inhibitors RIPK1, RIPK2, RIPK4 AOC3 4546/4885MEN1 3757/4885KMT2A 3048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.