SCHEMBL28679402

SCHEMBL28679402

C#CC(OC(C#C)c1ccc(F)cc1Br)c1ccc(F)cc1Br

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.33
APLNR P35414 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17514484 0.79 APLNR (0.30) APLNR
SCHEMBL24007262 0.76 APLNR (0.35) PKMAPLNR
SCHEMBL7266298 0.76 KDM4E (0.35)
SCHEMBL11174670 0.73 IDO1 (0.39)
SCHEMBL1337142 0.70 PKM (0.35) PKMAPLNR
SCHEMBL29890715 0.70 PKM (0.35) PKMAPLNR
SCHEMBL7081498 0.69 PDE2A (0.43) APLNR
SCHEMBL1345761 0.69 PDE2A (0.43) APLNR
SCHEMBL17766971 0.69 PDE2A (0.43) APLNR
SCHEMBL28678690 0.69 IDO1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109336829-B Aryl formamide compound containing 1,2, 3-triazole structure and application thereof 沈阳药科大学 2022-03-01 CN disclosed