Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.63 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | RORA | P35398 | 1/20 | 0.52 |
| ▸ | RORC | P51449 | 1/20 | 0.52 |
| ▸ | RORB | Q92753 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | USP8 | P40818 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28678563 | 0.87 | MAPT (0.61) | SCN5ASCN9AKMT2AMEN1RORA | |
| SCHEMBL28678568 | 0.87 | PTGS2 (0.52) | SCN5ASCN9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL28683479 | 0.84 | MEN1 (0.51) | KMT2AMEN1ALDH1A1GAAPTGER3 | |
| SCHEMBL28684491 | 0.84 | KMT2A (0.60) | SCN5ASCN9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL27179948 | 0.80 | MEN1 (0.60) | KMT2AMEN1RORARORCRORB | |
| SCHEMBL30926493 | 0.80 | MEN1 (0.60) | KMT2AMEN1RORARORCRORB | |
| SCHEMBL28685991 | 0.80 | RAB9A (0.59) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL19475865 | 0.79 | SCN9A (1.00) | SCN5ASCN9A | |
| SCHEMBL28702792 | 0.79 | MAPT (0.58) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL2200877 | 0.78 | KMT2A (0.53) | SCN5ASCN9AKMT2AMEN1RORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031630-A | Synthesis method of spiro thiophene sulfonamide compound | 福州大学 | 2022-02-11 | — | — | CN | disclosed |