Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28679405 | 0.87 | SCN5A (0.63) | MAPTALDH1A1KDM4EGAANPSR1 | |
| SCHEMBL28684491 | 0.85 | KMT2A (0.60) | MAPTALDH1A1KDM4EGAASCN5A | |
| SCHEMBL28683479 | 0.83 | MEN1 (0.51) | ALDH1A1GAATP53LMNAMEN1 | |
| SCHEMBL28678568 | 0.82 | PTGS2 (0.52) | MAPTALDH1A1KDM4EGAANPSR1 | |
| SCHEMBL28685991 | 0.82 | RAB9A (0.59) | MAPTALDH1A1KDM4ETP53LMNA | |
| SCHEMBL28702792 | 0.78 | MAPT (0.58) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL28703368 | 0.76 | HPGD (0.58) | ALDH1A1KDM4EGAATP53SCN5A | |
| SCHEMBL28704050 | 0.76 | FLT1 (0.58) | MAPTSCN5ASCN9ALMNAHTT | |
| SCHEMBL26704182 | 0.76 | LMNA (0.61) | ALDH1A1HDAC1LMNAHDAC3HDAC11 | |
| SCHEMBL18112599 | 0.75 | HDAC1 (0.56) | ALDH1A1KDM4EGAAHDAC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031630-A | Synthesis method of spiro thiophene sulfonamide compound | 福州大学 | 2022-02-11 | — | — | CN | disclosed |