Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28696288 | 0.92 | CACNA1B (0.53) | STAT3CACNA1BAPBA1MCL1KDM4E | |
| SCHEMBL28681436 | 0.91 | STAT3 (0.61) | STAT3CACNA1BAPBA1MCL1KDM4E | |
| SCHEMBL28695985 | 0.90 | STAT3 (0.55) | STAT3CACNA1BAPBA1MCL1KDM4E | |
| SCHEMBL28673399 | 0.89 | MEN1 (0.58) | STAT3CACNA1BAPBA1MCL1KDM4E | |
| SCHEMBL28699068 | 0.89 | STAT3 (0.54) | STAT3CACNA1BAPBA1MCL1KDM4E | |
| SCHEMBL28683183 | 0.89 | CHEK1 (0.58) | STAT3CACNA1BAPBA1MCL1KDM4E | |
| SCHEMBL28699093 | 0.87 | CTDSP1 (0.62) | STAT3CACNA1BAPBA1MCL1KDM4E | |
| SCHEMBL28673422 | 0.86 | MEN1 (0.59) | STAT3CACNA1BAPBA1MCL1KDM4E | |
| SCHEMBL28683197 | 0.86 | STAT3 (0.51) | STAT3CACNA1BAPBA1MCL1KDM4E | |
| SCHEMBL28690124 | 0.84 | ALDH1A1 (0.58) | STAT3CACNA1BAPBA1MCL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113747920-A | Immune checkpoint inhibitor combination therapy using quinoline carboxamide derivatives | 株式会社益力多本社 | 2021-12-03 | — | — | CN | disclosed |
| CN-112703001-A | Combination cancer therapy using quinoline carboxamide derivatives | 株式会社益力多本社 | 2021-04-23 | — | — | CN | disclosed |