SCHEMBL2867970

SCHEMBL2867970

O[C@@H](CCl)CNc1ccc(C2CNCCO2)c(F)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2867964 1.00
SCHEMBL28998623 0.90
SCHEMBL28692830 0.88
SCHEMBL28997910 0.86
SCHEMBL3944341 0.82 ALDH1A1 (0.47)
SCHEMBL3947352 0.82 ALDH1A1 (0.47)
SCHEMBL26156229 0.81
SCHEMBL26154082 0.75
SCHEMBL5216740 0.73
SCHEMBL324930 0.73 DRD2 (0.60)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015162622-A1 PROCESS FOR PREPARATION OF LINEZOLID VIRDEV INTERMEDIATES PVT. LTD. (IN) 2015-10-29 WO claimed
EP-2595968-B1 NOVEL PROCESS FOR PREPARATION OF LINEZOLID AND ITS NOVEL INTERMEDIATES LEE PHARMA LTD (IN) 2015-09-09 EP claimed
EP-1768967-B1 NOVEL INTERMEDIATES FOR LINEZOLID AND RELATED COMPOUNDS SYMED LABS LTD (IN) 2009-04-22 EP claimed
EP-1737850-B1 A NOVEL PROCESS FOR THE PREPARATION OF LINEZOLID AND RELATED COMPOUNDS SYMED LABS LTD (IN) 2007-10-03 EP claimed
WO-2010084514-A2 A PROCESS FOR THE PREPARATION OF (5S)-(N)-[[3-[3-FLUORO-4-(4-MORPHOLINYL) PHENYL]-2-OXO-5-OXAZOLIDINYL] METHYL] ACETAMIDE NEULAND LABORATORIES LTD. (IN) 2010-07-29 WO disclosed
EP-1768967-B1 NOVEL INTERMEDIATES FOR LINEZOLID AND RELATED COMPOUNDS SYMED LABS LTD (IN) 2009-04-22 EP disclosed
US-7429661-B2 Intermediates for linezolid and related compounds SYMED LABS LIMITED (IN) 2008-09-30 US disclosed
EP-1768967-A1 NOVEL INTERMEDIATES FOR LINEZOLID AND RELATED COMPOUNDS Symed Labs Limited (IN) 2007-04-04 EP disclosed
US-20060247435-A1 Novel intermediates for linezolid and related compounds HETERO USA, INC. (US) 2006-11-02 US disclosed
WO-2006008754-A1 NOVEL INTERMEDIATES FOR LINEZOLID AND RELATED COMPOUNDS SYMED LABS LIMITED (IN) 2006-01-26 WO disclosed