Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | FPR3 | P25089 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720671 | 0.84 | PDPK1 (0.46) | DGAT1PDPK1MEN1KMT2AMTNR1B | |
| SCHEMBL28681184 | 0.83 | AKR1B1 (0.39) | AKR1B1LMNANPC1PARP10 | |
| SCHEMBL29086718 | 0.81 | LMNA (0.38) | MEN1KMT2ALMNA | |
| SCHEMBL29086611 | 0.81 | ALOX5 (0.37) | DGAT1LMNA | |
| SCHEMBL28688751 | 0.79 | LMNA (0.36) | DGAT1LMNANPC1 | |
| SCHEMBL28681205 | 0.79 | LMNA (0.36) | MEN1KMT2ALMNANPC1 | |
| SCHEMBL26938435 | 0.79 | PDPK1 (0.56) | DGAT1PDPK1MTNR1BNPC1FPR2 | |
| SCHEMBL15087374 | 0.77 | TAAR1 (0.52) | LMNAPARP15PARP10 | |
| SCHEMBL31551664 | 0.75 | DGAT1 (0.55) | DGAT1PDPK1MEN1KMT2AAKR1B1 | |
| SCHEMBL538344 | 0.75 | DGAT1 (0.55) | DGAT1PDPK1MEN1KMT2AAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-B | Thienopyridine carboxamides as ubiquitin-specific protease inhibitors | 瓦洛健康公司 | 2022-01-14 | — | — | CN | disclosed |