Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19212239 | 0.82 | MAPT (0.57) | GPR119ALDH1A1LMNAMAPTNAMPT | |
| SCHEMBL28691653 | 0.80 | ALDH1A1 (0.42) | HDAC6PDE4BHDAC8GPR119ALDH1A1 | |
| SCHEMBL38661632 | 0.79 | HDAC6 (0.46) | HDAC6HDAC8GPR119ALDH1A1SMARCA2 | |
| SCHEMBL4154819 | 0.79 | CNR1 (0.48) | HDAC6HDAC8LMNACNR1 | |
| SCHEMBL28582864 | 0.78 | GPR119 (0.52) | HDAC6PDE4BHDAC8GPR119ALDH1A1 | |
| SCHEMBL4177222 | 0.78 | CNR1 (0.47) | HDAC6PDE4BHDAC8GPR119ALDH1A1 | |
| SCHEMBL38661618 | 0.77 | MEN1 (0.46) | HDAC6HDAC8GPR119LMNACNR1 | |
| SCHEMBL5377546 | 0.76 | HDAC6 (0.43) | HDAC6PDE4BHDAC8GPR119MAPT | |
| SCHEMBL13699555 | 0.74 | HTT (0.52) | GPR119ALDH1A1LMNAMAPTNAMPT | |
| SCHEMBL4163959 | 0.74 | NR1D1 (0.46) | HDAC6GPR119ALDH1A1LMNACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-B | Thienopyridine carboxamides as ubiquitin-specific protease inhibitors | 瓦洛健康公司 | 2022-01-14 | — | — | CN | disclosed |