Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29271806 | 1.00 | PRKCA (0.37) | PRKCAGBA1MAPTMAPK1 | |
| SCHEMBL27910728 | 0.85 | PRKCA (0.37) | PRKCAGBA1MAPTMAPK1 | |
| SCHEMBL27910718 | 0.84 | CTSK (0.38) | GBA1 | |
| SCHEMBL27834093 | 0.84 | CTSK (0.38) | GBA1 | |
| SCHEMBL27648605 | 0.84 | CTSK (0.38) | PRKCAGBA1 | |
| SCHEMBL28773695 | 0.84 | CTSK (0.38) | PRKCAGBA1 | |
| SCHEMBL28670288 | 0.84 | PRKCA (0.36) | PRKCAGBA1 | |
| SCHEMBL27726431 | 0.84 | CTSK (0.38) | GBA1 | |
| SCHEMBL29273401 | 0.83 | PRKCA (0.38) | PRKCAGBA1MAPTMAPK1 | |
| SCHEMBL27696914 | 0.83 | CPB2 (0.34) | PRKCAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922394-B | 3-tetrazolyl-benzene-1, 2-disulfonamide derivatives as metallo-beta-lactamase inhibitors | 默沙东公司 | 2021-07-13 | — | — | CN | disclosed |