SCHEMBL28680213

SCHEMBL28680213

COCCOCCC=C(C#N)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.35
KMT2A Q03164 3/20 0.35
KDM4E B2RXH2 3/20 0.35
PKM P14618 1/20 0.35
APP P05067 3/20 0.34
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 2/20 0.33
MITF O75030 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
MDM2 Q00987 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28672469 0.90 LMNA (0.33) LMNAKMT2AKDM4EPKMAPP
SCHEMBL29402 0.90 LMNA (0.38) LMNAKMT2AKDM4EPKMALDH1A1
SCHEMBL28667711 0.87 POLB (0.33) LMNAKMT2AKDM4EPKMPOLB
SCHEMBL28676504 0.87 ALDH1A1 (0.36) LMNAKMT2AKDM4EPKMALDH1A1
SCHEMBL3240748 0.85 CYP2C9 (0.33) LMNAKMT2AKDM4EPKMPOLB
SCHEMBL28681588 0.84 ZDHHC20 (0.38) KMT2AMEN1POLB
SCHEMBL30580 0.83 CYP2C9 (0.38) LMNAKMT2AKDM4EPKMALDH1A1
SCHEMBL718912 0.83 ALDH1A1 (0.38) LMNAKMT2AKDM4EPKMALDH1A1
SCHEMBL28666287 0.83 ZDHHC20 (0.43) KMT2AMEN1POLBMAPT
SCHEMBL2406321 0.82 ZDHHC20 (0.39) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113874459-B Flexible photocurable cyanoacrylate compositions 汉高股份有限及两合公司 2023-07-04 CN disclosed
CN-113874459-A Flexible photocurable cyanoacrylate compositions 汉高知识产权控股有限责任公司 2021-12-31 CN disclosed