Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30887665 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ACASP3KDM4E | |
| SCHEMBL28680301 | 0.84 | CASP3 (0.56) | ALDH1A1MEN1KMT2ACASP3KDM4E | |
| SCHEMBL28688250 | 0.67 | MAPT (0.36) | ALDH1A1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL30887637 | 0.67 | MAPT (0.36) | ALDH1A1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL12202083 | 0.66 | CASP3 (0.45) | ALDH1A1MEN1KMT2ACASP3KDM4E | |
| SCHEMBL8654624 | 0.65 | GAA (0.45) | ALDH1A1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL9208732 | 0.64 | CASP3 (0.66) | ALDH1A1CASP3KDM4ECHRM2CHRM4 | |
| SCHEMBL30671499 | 0.64 | KDM4E (0.37) | ALDH1A1MEN1KMT2AKDM4ECHRM2 | |
| SCHEMBL1280809 | 0.63 | HSD17B10 (0.54) | ALDH1A1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL24970169 | 0.62 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113135924-B | Pyrimidine derivatives and their use in medicine | 广东东阳光药业股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-113135924-A | Pyrimidine derivatives and their use in medicine | 广东东阳光药业有限公司 | 2021-07-20 | — | — | CN | disclosed |