SCHEMBL28680577

SCHEMBL28680577

CC(c1ccccc1)C1([SiH3])CCCCO1.[H+]

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.32
HPGD P15428 1/20 0.32
OPRM1 P35372 2/20 0.32
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 2/20 0.31
TSHR P16473 2/20 0.31
ADRA2A P08913 1/20 0.31
ADRA2C P18825 1/20 0.31
CYP2D6 P10635 1/20 0.31
HIF1A Q16665 1/20 0.31
KDM4E B2RXH2 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
ALOX15 P16050 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28255106 0.84
SCHEMBL28119517 0.83 MEN1 (0.33) OPRM1MEN1POLBKMT2A
SCHEMBL17024087 0.83 OPRM1 (0.33) LMNAHPGDOPRM1MEN1POLB
SCHEMBL27736162 0.82
SCHEMBL28009306 0.81 MEN1 (0.33) OPRM1MEN1POLBKMT2AALDH1A1
SCHEMBL3219070 0.81 MEN1 (0.33) MEN1POLBKMT2AALDH1A1TSHR
SCHEMBL27597468 0.80
SCHEMBL28497539 0.79 L3MBTL1 (0.33) LMNAHPGDMEN1POLBKMT2A
SCHEMBL10479149 0.79 TSHR (0.33) MEN1POLBKMT2ATSHR
SCHEMBL28520181 0.78 ALDH1A1 (0.37) LMNAOPRM1ALDH1A1TSHRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117965032-A High-hardness polysiloxane scintillator and preparation method and application thereof 湘潭大学 2024-05-03 CN claimed
CN-113999529-B Polysiloxane-based plastic scintillator and preparation method and application thereof 湘潭大学 2023-07-14 CN claimed
CN-113999529-A Polysiloxane-based plastic scintillator and preparation method and application thereof 湘潭大学 2022-02-01 CN claimed
CN-117965032-A High-hardness polysiloxane scintillator and preparation method and application thereof 湘潭大学 2024-05-03 CN disclosed
CN-114716830-B Plastic scintillator and preparation method and application thereof 湘潭大学 2023-08-11 CN disclosed
CN-113999529-B Polysiloxane-based plastic scintillator and preparation method and application thereof 湘潭大学 2023-07-14 CN disclosed
CN-114716830-A Plastic scintillator and preparation method and application thereof 湘潭大学 2022-07-08 CN disclosed
CN-113999529-A Polysiloxane-based plastic scintillator and preparation method and application thereof 湘潭大学 2022-02-01 CN disclosed
CN-113999529-A Polysiloxane-based plastic scintillator and preparation method and application thereof 湘潭大学 2022-02-01 CN disclosed
CN-103703088-B Temporary bonding of chemically similar substrates WACKER CHEMIE AG (DE) 2015-10-14 CN disclosed