SCHEMBL28680608

SCHEMBL28680608

Cc1ccccc1OP(=O)(O)OOC(=O)c1ccc(CC(C)C)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
RXRG P48443 1/20 0.40
TDP1 Q9NUW8 4/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
MAPT P10636 3/20 0.37
LMNA P02545 2/20 0.37
RAB9A P51151 1/20 0.37
ATM Q13315 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
POLB P06746 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
KDM4E B2RXH2 1/20 0.34
EPHX2 P34913 1/20 0.34
LPAR1 Q92633 1/20 0.34
LPAR5 Q9H1C0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28931849 0.89 RXRA (0.40) RXRARXRBRXRGTDP1L3MBTL1
SCHEMBL28931669 0.88 RXRA (0.43) RXRARXRBRXRGTDP1L3MBTL1
SCHEMBL28696137 0.85 TDP1 (0.43) RXRARXRBRXRGTDP1L3MBTL1
SCHEMBL28698180 0.85 RXRA (0.40) RXRARXRBRXRGTDP1L3MBTL1
SCHEMBL28698447 0.84 HPGD (0.40) RXRARXRBRXRGTDP1L3MBTL1
SCHEMBL28680419 0.84 F2 (0.46) RXRARXRBRXRGTDP1L3MBTL1
SCHEMBL28690473 0.83 TRPV1 (0.43) RXRARXRBRXRGMEN1KMT2A
SCHEMBL28687688 0.82 LMNA (0.39) TDP1MAPTLMNAMEN1KMT2A
SCHEMBL28693257 0.80 NPSR1 (0.42) TDP1L3MBTL1MAPTLMNARAB9A
SCHEMBL28698431 0.78 PTGS1 (0.42) LMNAMEN1KMT2ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114085301-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2022-02-25 CN claimed
CN-113929797-A Solid catalyst component and catalyst system for producing polymers 中国石油化工股份有限公司 2022-01-14 CN claimed
CN-113929798-A Solid catalyst component and catalyst system for olefin polymerization 中国石油化工股份有限公司 2022-01-14 CN claimed
CN-113929799-A Catalyst component for olefin polymerization, catalyst system and application 中国石油化工股份有限公司 2022-01-14 CN claimed
CN-114085301-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2022-02-25 CN disclosed
CN-113929797-A Solid catalyst component and catalyst system for producing polymers 中国石油化工股份有限公司 2022-01-14 CN disclosed
CN-113929798-A Solid catalyst component and catalyst system for olefin polymerization 中国石油化工股份有限公司 2022-01-14 CN disclosed
CN-113929799-A Catalyst component for olefin polymerization, catalyst system and application 中国石油化工股份有限公司 2022-01-14 CN disclosed