SCHEMBL28931669

SCHEMBL28931669

CCc1ccc(C(=O)OOP(=O)(O)Oc2ccccc2C)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
RXRG P48443 1/20 0.43
RAB9A P51151 3/20 0.41
NPC1 O15118 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
MAPT P10636 3/20 0.40
LMNA P02545 2/20 0.40
SMN1; SMN2 Q16637 4/20 0.38
ALDH1A1 P00352 4/20 0.38
HTT P42858 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP2C19 P33261 1/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
POLB P06746 1/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
TAOK1 Q7L7X3 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28698180 0.91 RXRA (0.40) RXRARXRBRXRGRAB9ANPC1
SCHEMBL28696137 0.89 TDP1 (0.43) RXRARXRBRXRGRAB9ANPC1
SCHEMBL28690473 0.89 TRPV1 (0.43) RXRARXRBRXRGMEN1KMT2A
SCHEMBL28680608 0.88 RXRA (0.40) RXRARXRBRXRGRAB9AL3MBTL1
SCHEMBL28680419 0.88 F2 (0.46) RXRARXRBRXRGRAB9ANPC1
SCHEMBL28698447 0.84 HPGD (0.40) RXRARXRBRXRGL3MBTL1TDP1
SCHEMBL28693257 0.84 NPSR1 (0.42) RAB9ANPC1L3MBTL1TDP1MAPT
SCHEMBL28672554 0.80 CYP2C19 (0.51) RXRARXRBTDP1MAPTLMNA
SCHEMBL28673147 0.78 MAPT (0.40) RXRARXRBRXRGTDP1MAPT
SCHEMBL29018272 0.76 ALDH1A1 (0.50) RXRARXRBNPC1TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114085301-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2022-02-25 CN claimed
CN-113929797-A Solid catalyst component and catalyst system for producing polymers 中国石油化工股份有限公司 2022-01-14 CN claimed
CN-113929799-A Catalyst component for olefin polymerization, catalyst system and application 中国石油化工股份有限公司 2022-01-14 CN claimed
CN-113929798-A Solid catalyst component and catalyst system for olefin polymerization 中国石油化工股份有限公司 2022-01-14 CN claimed
CN-114085301-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2022-02-25 CN disclosed
CN-113929797-A Solid catalyst component and catalyst system for producing polymers 中国石油化工股份有限公司 2022-01-14 CN disclosed
CN-113929798-A Solid catalyst component and catalyst system for olefin polymerization 中国石油化工股份有限公司 2022-01-14 CN disclosed
CN-113929799-A Catalyst component for olefin polymerization, catalyst system and application 中国石油化工股份有限公司 2022-01-14 CN disclosed