SCHEMBL28680640

SCHEMBL28680640

Nc1ccc2ccc3c(N)c(-c4ccc(-c5ccccc5)cc4)cc4ccc1c2c43

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.36
HSD17B10 Q99714 3/20 0.36
ALDH1A1 P00352 2/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
KDM4E B2RXH2 3/20 0.35
MAPT P10636 3/20 0.35
MEN1 O00255 2/20 0.35
HPGD P15428 2/20 0.35
KMT2A Q03164 2/20 0.35
CYP1A2 P05177 2/20 0.35
ACHE P22303 2/20 0.35
USP2 O75604 1/20 0.35
LMNA P02545 1/20 0.35
HSP90AA1 P07900 1/20 0.35
GAA P10253 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28115335 0.97 ALDH1A1 (0.38) DHFRHSD17B10ALDH1A1CRHBPCRHR2
SCHEMBL28188087 0.97 ALDH1A1 (0.38) DHFRHSD17B10ALDH1A1CRHBPCRHR2
SCHEMBL28982412 0.91 KEAP1 (0.38) DHFRHSD17B10ALDH1A1CRHBPCRHR2
SCHEMBL27950895 0.85 CYP1A2 (0.50) HSD17B10ALDH1A1KDM4EMAPTMEN1
SCHEMBL28743028 0.85 ALDH1A1 (0.34) DHFRHSD17B10ALDH1A1KDM4EMAPT
SCHEMBL27999016 0.85 AAK1 (0.41) IKBKBCYP3A4JAK2CHUK
SCHEMBL22589048 0.84 MEN1 (0.39) HSD17B10ALDH1A1KDM4EMAPTMEN1
SCHEMBL28344890 0.84 MEN1 (0.31) MEN1KMT2ATDP1
SCHEMBL28418565 0.82 MAPT (0.41) HSD17B10ALDH1A1CRHBPCRHR2KEAP1
SCHEMBL19812481 0.82 MEN1 (0.42) CRHBPCRHR2KEAP1NFE2L2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113845479-B Dibenzazepine compound used in organic layer of OLED device and organic electroluminescent device 京东方科技集团股份有限公司 2023-10-27 CN claimed
CN-118076132-A WOLED device and display device 京东方科技集团股份有限公司 2024-05-24 CN disclosed
CN-118077329-A Aromatic amine compound and application thereof, electroluminescent device and display device 京东方科技集团股份有限公司 2024-05-24 CN disclosed
CN-117750807-A Display substrate, display device and manufacturing method 京东方科技集团股份有限公司 2024-03-22 CN disclosed
CN-117486891-A Aromatic amine compound, electroluminescent device and display device 京东方科技集团股份有限公司 2024-02-02 CN disclosed
CN-115210895-B Organic light emitting diode and display panel 京东方科技集团股份有限公司 2023-12-22 CN disclosed
CN-117178661-A Light emitting device and display apparatus 京东方科技集团股份有限公司 2023-12-05 CN disclosed
CN-117177602-A Display panel and display device 京东方科技集团股份有限公司 2023-12-05 CN disclosed
CN-117063630-A Display panel and display device 京东方科技集团股份有限公司 2023-11-14 CN disclosed
CN-113845479-B Dibenzazepine compound used in organic layer of OLED device and organic electroluminescent device 京东方科技集团股份有限公司 2023-10-27 CN disclosed
CN-115073516-A Phosphorus-oxygen-based derivative, application, organic electroluminescent device and display device 京东方科技集团股份有限公司 2022-09-20 CN disclosed
CN-115043738-A Arylamine compound, light-emitting device and display device 京东方科技集团股份有限公司 2022-09-13 CN disclosed
CN-114930562-A Organic electroluminescent device and display apparatus 京东方科技集团股份有限公司 2022-08-19 CN disclosed
CN-114874176-A Heterocyclic compound, application and organic electroluminescent device 京东方科技集团股份有限公司 2022-08-09 CN disclosed
CN-114853816-A Metal complex, organic electroluminescent device comprising same and display device 京东方科技集团股份有限公司 2022-08-05 CN disclosed
CN-114702508-A Triazine derivative, light-emitting device and display device 京东方科技集团股份有限公司 2022-07-05 CN disclosed
CN-114702394-A Spiro compound, preparation method thereof, hole transport material and light emitting device 京东方科技集团股份有限公司 2022-07-05 CN disclosed
CN-114573538-A Arylamine compound, light-emitting device and display device 京东方科技集团股份有限公司 2022-06-03 CN disclosed
CN-113845479-A Dibenzoazepine compound used in organic layer of OLED device and organic electroluminescent device 京东方科技集团股份有限公司 2021-12-28 CN disclosed
CN-113540374-A Light emitting device, display panel and display apparatus 京东方科技集团股份有限公司 2021-10-22 CN disclosed