SCHEMBL28115335

SCHEMBL28115335

Nc1ccc2ccc3c(N)c(-c4ccccc4)cc4ccc1c2c43

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
HSD17B10 Q99714 1/20 0.38
KEAP1 Q14145 2/20 0.38
NFE2L2 Q16236 2/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
ACHE P22303 3/20 0.37
ERBB2 P04626 1/20 0.37
CYP1A2 P05177 1/20 0.37
FYN P06241 1/20 0.37
MAOA P21397 1/20 0.37
AHR P35869 1/20 0.37
NPC1 O15118 1/20 0.36
KDM4E B2RXH2 3/20 0.34
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
CDK4 P11802 1/20 0.34
CCND1 P24385 1/20 0.34
HPRT1 P00492 1/20 0.33
FGFR1 P11362 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28188087 1.00 ALDH1A1 (0.38) ALDH1A1HSD17B10KEAP1NFE2L2CRHBP
SCHEMBL28680640 0.97 DHFR (0.36) ALDH1A1HSD17B10KEAP1NFE2L2CRHBP
SCHEMBL28982412 0.91 KEAP1 (0.38) ALDH1A1HSD17B10KEAP1NFE2L2CRHBP
SCHEMBL27950895 0.88 CYP1A2 (0.50) ALDH1A1HSD17B10ACHEERBB2CYP1A2
SCHEMBL28344890 0.84 MEN1 (0.31) KMT2AMEN1
SCHEMBL22589048 0.84 MEN1 (0.39) ALDH1A1HSD17B10MAOANPC1KDM4E
SCHEMBL1666830 0.83 MAOB (0.40) ALDH1A1HSD17B10KEAP1NFE2L2FYN
SCHEMBL29444827 0.83 MAOB (0.40) ALDH1A1HSD17B10KEAP1NFE2L2FYN
SCHEMBL29127881 0.83 KEAP1 (0.38) ALDH1A1HSD17B10KEAP1NFE2L2CRHBP
SCHEMBL28743028 0.82 ALDH1A1 (0.34) ALDH1A1HSD17B10CYP1A2KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109180585-A Luminous organic material and preparation method thereof and organic electroluminescence device containing the material 吉林奥来德光电材料股份有限公司 2019-01-11 CN disclosed
CN-106336360-A COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY DEVICE INCLUDING SAME 三星显示有限公司 2017-01-18 CN disclosed