SCHEMBL28680684

SCHEMBL28680684

CCCCc1c(C(=O)O)cccc1C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.41
CA9 Q16790 3/20 0.41
TSHR P16473 1/20 0.41
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.40
RECQL P46063 1/20 0.40
KMT2A Q03164 1/20 0.40
GABRP O00591 1/20 0.40
GABRD O14764 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRB1 P18505 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40
GABRB2 P47870 1/20 0.40
GABRA4 P48169 1/20 0.40
GABRE P78334 1/20 0.40
GABRA6 Q16445 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8878225 0.89 CA12 (0.40) CA12CA9TSHRKDM4EMEN1
SCHEMBL27486467 0.86 TAS2R14 (0.49) TSHRKDM4EMEN1RECQLKMT2A
SCHEMBL9047787 0.86 ALOX15 (0.38) TSHRKDM4EGABRA1GABRB2ALOX15
SCHEMBL679426 0.85 TSHR (0.49) CA12CA9TSHRKDM4EMEN1
SCHEMBL10841768 0.84 TSHR (0.40) TSHRKDM4EMEN1RECQLKMT2A
SCHEMBL27976077 0.83 TSHR (0.47) CA12CA9TSHRKDM4EMEN1
SCHEMBL28197780 0.81 PLK1 (0.50) PLK1TAS2R14RARBBIDBCL2L1
SCHEMBL6859420 0.80 KDM4E (0.52) CA12CA9TSHRKDM4EMEN1
SCHEMBL16418617 0.80 ALOX15 (0.43) CA12CA9TSHRKDM4EGABRA1
SCHEMBL27297604 0.80 PLK1 (0.50) CA12CA9TSHRPLK1RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113754521-A Synthetic process method of avobenzone 马鞍山科思化学有限公司 2021-12-07 CN claimed