Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047730 | 0.88 | CA2 (0.35) | ALDH1A1KDM4EMRGPRX4CA2GABRA1 | |
| SCHEMBL28680684 | 0.86 | CA12 (0.41) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9046662 | 0.82 | CA2 (0.41) | ALDH1A1CA2GABRA1GABRB2TSHR | |
| SCHEMBL9045316 | 0.81 | HPGD (0.50) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL16418617 | 0.79 | ALOX15 (0.43) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9047115 | 0.78 | CLCN2 (0.45) | ALDH1A1KDM4EHPGDHSD17B10MRGPRX4 | |
| SCHEMBL319241 | 0.78 | ALOX15 (0.42) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2207015 | 0.78 | ALOX15 (0.42) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9044072 | 0.77 | GABRA1 (0.46) | ALDH1A1KDM4ECA2GABRA1GABRB2 | |
| SCHEMBL9046401 | 0.76 | TSHR (0.50) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690854-A1 | 1-PHENYL-IMIDAZOL-2-ONE BIPHENYLMETHYL COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1996-01-10 | — | — | EP | claimed |