Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28680772 | 0.91 | NR4A2 (0.49) | NR4A2MAOBHCAR2KDM4EMAPT | |
| SCHEMBL7809052 | 0.85 | NR4A2 (0.53) | NR4A2MAOBHCAR2PARP10PPARA | |
| SCHEMBL360528 | 0.84 | NR4A2 (0.55) | NR4A2MAOBHCAR2PARP10PPARA | |
| SCHEMBL657234 | 0.84 | TDP1 (0.55) | KDM4ECYP1A2MAPTCYP2C9MAPK1 | |
| SCHEMBL27622766 | 0.83 | LMNA (0.60) | NR4A2MAOBKDM4EMAPTLMNA | |
| SCHEMBL4888735 | 0.82 | NR4A2 (0.56) | NR4A2MAOBHCAR2IDO1AGXT | |
| SCHEMBL8888362 | 0.79 | MRGPRX4 (0.57) | MAOBIDO1AGXTCYP1A2MRGPRX4 | |
| SCHEMBL11439089 | 0.79 | LOXL2 (0.57) | KDM4EMAPTMRGPRX4LMNARAB9A | |
| SCHEMBL570730 | 0.79 | MAPT (0.51) | NR4A2MAPTL3MBTL1GPR52RAB9A | |
| SCHEMBL7646959 | 0.78 | MEN1 (0.54) | NR4A2HCAR2PPARAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109020883-B | 3-cyano-2-aminopyridine derivative and preparation method and application thereof | 广西民族大学 | 2022-02-08 | — | — | CN | disclosed |