Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH1 | P20839 | 4/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | NEK2 | P51955 | 1/20 | 0.30 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28680727 | 0.83 | IMPDH1 (0.34) | IMPDH1IMPDH2CYP1A1KCNJ1KCNH2 | |
| SCHEMBL28659570 | 0.83 | CA2 (0.35) | IMPDH1IMPDH2CYP1A1KCNJ1KCNH2 | |
| SCHEMBL28670661 | 0.77 | IMPDH1 (0.39) | IMPDH1IMPDH2CYP1A1NUAK1IGF1R | |
| SCHEMBL12553493 | 0.77 | IMPDH1 (0.39) | IMPDH1IMPDH2CYP1A1KCNJ1KCNH2 | |
| SCHEMBL30823442 | 0.75 | MAOA (0.37) | IMPDH1IMPDH2CYP1A1KCNJ1KCNH2 | |
| SCHEMBL30823443 | 0.75 | MAOA (0.37) | IMPDH1IMPDH2CYP1A1KCNJ1KCNH2 | |
| SCHEMBL29118352 | 0.75 | MAOA (0.37) | IMPDH1IMPDH2CYP1A1KCNJ1KCNH2 | |
| SCHEMBL28670654 | 0.74 | MMP2 (0.36) | IMPDH1IMPDH2CYP1A1 | |
| Water SCHEMBL31162594 | 0.74 | MAOA (0.36) | IMPDH1IMPDH2 | |
| SCHEMBL12553463 | 0.72 | MAOA (0.47) | CYP1A1NUAK1IGF1RMETPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113666895-A | Halogenated 2-benzo [ c ] furanone compound and application thereof | 华北制药集团新药研究开发有限责任公司 | 2021-11-19 | — | — | CN | claimed |
| CN-113666895-A | Halogenated 2-benzo [ c ] furanone compound and application thereof | 华北制药集团新药研究开发有限责任公司 | 2021-11-19 | — | — | CN | disclosed |