Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28687598 | 0.85 | LMNA (0.52) | LMNASMN1; SMN2HTTTRPM8IDO1 | |
| SCHEMBL22957446 | 0.83 | SMN1; SMN2 (0.50) | LMNASMN1; SMN2HTTTRPM8IDO1 | |
| SCHEMBL29707309 | 0.82 | LMNA (0.52) | LMNASMN1; SMN2HTTTRPM8IDO1 | |
| SCHEMBL19210898 | 0.82 | LMNA (0.52) | LMNASMN1; SMN2HTTTRPM8IDO1 | |
| SCHEMBL6560301 | 0.82 | LMNA (0.52) | LMNASMN1; SMN2HTTTRPM8IDO1 | |
| SCHEMBL6558252 | 0.81 | LMNA (0.50) | LMNASMN1; SMN2HTTTRPM8IDO1 | |
| SCHEMBL19212041 | 0.81 | PTGDR2 (0.51) | LMNASMN1; SMN2HTTTRPM8IDO1 | |
| SCHEMBL3626674 | 0.79 | LMNA (0.53) | LMNASMN1; SMN2HTTTRPM8IDO1 | |
| SCHEMBL29707336 | 0.78 | SMN1; SMN2 (0.52) | LMNASMN1; SMN2HTTTRPM8IDO1 | |
| SCHEMBL28680864 | 0.75 | PTGDR2 (0.49) | LMNASMN1; SMN2HTTIDO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-B | Thienopyridine carboxamides as ubiquitin-specific protease inhibitors | 瓦洛健康公司 | 2022-01-14 | — | — | CN | disclosed |