Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28723370 | 0.82 | LMNA (0.34) | HTR4CHRM3CARM1PRMT6ALOX15 | |
| SCHEMBL16844987 | 0.82 | NCF1 (0.43) | NCF1HTR4HDAC1HDAC2HDAC3 | |
| SCHEMBL16884955 | 0.81 | NCF1 (0.44) | NCF1HTR4HDAC1HDAC2HDAC3 | |
| SCHEMBL28999355 | 0.81 | HDAC3 (0.44) | HDAC1HDAC2HDAC3GAA | |
| SCHEMBL28037383 | 0.81 | SMN1; SMN2 (0.55) | HTR4CHRM3CARM1PRMT6ALOX15 | |
| SCHEMBL30427433 | 0.81 | PARP15 (0.42) | CHRM3ALOX15 | |
| SCHEMBL111361 | 0.81 | — | — | |
| SCHEMBL20656958 | 0.81 | HTR4 (0.44) | NCF1HTR4HDAC1HDAC2HDAC3 | |
| SCHEMBL28949431 | 0.81 | GAA (0.40) | HDAC1HDAC2HDAC3CHRM3CARM1 | |
| SCHEMBL4231380 | 0.80 | CARM1 (0.41) | HTR4CHRM3CARM1PRMT6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113891745-B | As P2X3Aminoquinazoline derivatives of inhibitors | 奇斯药制品公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-116802184-A | Pyrazolothiazole carboxamides and their use as PDGFR inhibitors | 埃科特莱茵药品有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116601149-A | Aminoquinazoline derivatives as P2X3 inhibitors | 奇斯药制品公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-116096719-A | Pyridazinylamino derivatives as ALK5 inhibitors | 奇斯药制品公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-113891745-A | As P2X3Aminoquinazoline derivatives as inhibitors | 奇斯药制品公司 | 2022-01-04 | — | — | CN | disclosed |