SCHEMBL28683052

SCHEMBL28683052

CC(O)COc1cccc(-c2cccc3c2Cc2ccccc2-3)c1Cc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
ABCB1 P08183 9/20 0.37
CARM1 Q86X55 1/20 0.36
PNMT P11086 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
TLR4 O00206 1/20 0.33
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
HTR7 P34969 1/20 0.33
HTR2B P41595 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28696289 0.82 LMNA (0.40) LMNAABCB1PNMTNPC1RAB9A
SCHEMBL28684140 0.78 KDM4E (0.38) LMNAABCB1PNMTNPC1RAB9A
SCHEMBL28683049 0.76 LMNA (0.42) LMNACARM1PNMTNPC1RAB9A
SCHEMBL23214351 0.75 LMNA (0.41) LMNAABCB1
SCHEMBL28514622 0.74 NR2E1 (0.41) LMNAABCB1PNMTNPC1RAB9A
SCHEMBL28348127 0.74 KMT2A (0.36) LMNAPNMTNPC1RAB9ATLR4
SCHEMBL2806274 0.74 LMNA (0.50) LMNAPNMTNPC1RAB9APRMT5
SCHEMBL28519699 0.74 ADRB2 (0.35) LMNAPNMTNPC1RAB9ATLR4
SCHEMBL30493148 0.72 LMNA (0.44) LMNAPNMTNPC1RAB9APRMT5
SCHEMBL28525858 0.72 USP2 (0.36) LMNAPNMTNPC1RAB9ATLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114096611-A Epoxy resin composition 株式会社KCC 2022-02-25 CN disclosed